Details of the Metabolic Reaction (MR)
| General Information of This Metabolic Reaction (MR) (ID: MR005466) | ||||||
|---|---|---|---|---|---|---|
| Formula | ||||||
| Reactant | Capmatinib | Product | Capmatinib M19 | |||
| Reactant Info | Product Info | |||||
| Metabolic Enzyme | Xanthine dehydrogenase/oxidase (XDH) | DME Info | ||||
| Aldehyde oxidase (AOX1) | DME Info | |||||
| Other MR(s) Related to The Reactant of This MR | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Other MR(s) That Metabolize The Reactant of This MR | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| References | ||||||
|---|---|---|---|---|---|---|
| 1 | Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite | |||||
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