Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005844)
Formula
SVG example
Reactant Medazepam Product Diazepam
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005838 Medazepam Medazepam metabolite Oxidation - N-demethylation Medazepam [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001325 Ketazolam Diazepam Oxidation - Degradation Ketazolam [3]
References
1 Metabolism of 14C-medazepam hydrochloride in dog, rat and man
2 Further studies on medazepam metabolism in the rat
3 Urinary diazepam metabolite distribution in a chronic pain population J Anal Toxicol. 2014 Apr;38(3):135-42. doi: 10.1093/jat/bku001.

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