Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006040)
Formula Reactant Bendamustine Product Beta-hydroxybendamustine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006038 Bendamustine -hydroxybendamustine (Bendamustine metabolite M3) Oxidation - Hydrolyzationn Bendamustine [1]
MR006036 Bendamustine Monohydroxy-bendamustine (bendamustine metabolite HP1) Hydrolysis - Hydrolysis Bendamustine [1]
MR006039 Bendamustine N-desmethyl-bendamustine (Bendamustine metabolite M4) Oxidation - Dealkylation Bendamustine [1]
References
1 Pharmacokinetic and pharmacodynamic profile of bendamustine and its metabolites. Cancer Chemother Pharmacol. 2015 Jun;75(6):1143-54.

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