Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006292)
Formula Reactant Eugenol Product Quinone methide
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006294 Eugenol 3-piperidyl-1-(3'-methoxy-4'-hydroxyphenyl)-1-propanone Unclear Eugenol [1]
MR006295 Eugenol 3-pyrrolidinyl-1-(3'-methoxy-4'-hydroxyphenyl)-1-propanone Unclear Eugenol [1]
MR006293 Eugenol Glucuronic acid conjugate Unclear Eugenol [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013351 O-demethylated tetrandrine Quinone methide Unclear CBT-1 [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013352 Quinone methide O-demethylated tetrandrine GSH conjugate Unclear CBT-1 [3]
References
1 PubChem:Eugenol
2 Metabolism and cytotoxicity of eugenol in isolated rat hepatocytes
3 CYP3A5 mediates bioactivation and cytotoxicity of tetrandrine. Arch Toxicol. 2016 Jul;90(7):1737-48.

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