Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006399)
Formula Reactant Hydroxytriptolide Product Hydroxytriptolide glutathione
Reactant Info Product Info
Metabolic Enzyme Glutathione S-transferase (GST) DME Info
Metabolic Type Conjugation - Conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006395 PG-490 Hydroxytriptolide Oxidation - Hydrolyzationn PG-490 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006398 Hydroxytriptolide Hydroxytriptolide glucuronoside Conjugation - Conjugation PG-490 [1]
MR006400 Hydroxytriptolide Hydroxytriptolide sulfate Conjugation - Conjugation PG-490 [1]
MR006396 Hydroxytriptolide Trihydroxytriptolide Unclear PG-490 [1]
References
1 Preclinical pharmacokinetics of triptolide: a potential antitumor drug. Curr Drug Metab. 2019;20(2):147-154.

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