Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR006560)
Formula	UGT1A4 ... Glucuronidation
	Reactant	Hydrolytic-deaminated clofazimine		Product	Hydrolytic-deaminated clofazimine glucuronide
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	UDP-glucuronosyltransferase 1A4 (UGT1A4)					DME Info
	UDP-glucuronosyltransferase 1A9 (UGT1A9)					DME Info
	UDP-glucuronosyltransferase 1A3 (UGT1A3)					DME Info
	UDP-glucuronosyltransferase 2B4 (UGT2B4)					DME Info
Metabolic Type	Conjugation - Glucuronidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR006559	Clofazimine	Hydrolytic-deaminated clofazimine	Hydrolysis - Hydrolytic Deamination	Clofazimine	[1]

References
1	Characterization of Clofazimine Metabolism in Human Liver Microsomal Incubation In Vitro

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