Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006590)
Formula Reactant Clonidine Product 4-oxoclonidine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006588 Clonidine 2,6-dichlorophenylguanidine Unclear Clonidine [1]
MR006589 Clonidine 4,5-dehydroclonidine Unclear Clonidine [1]
MR006587 Clonidine 4-Hydroxyclonidine Oxidation - 4-hydroxylation Clonidine [2]
References
1 The metabolism of N,N'-dimethylclonidine by rat liver microsomes [proceedings]
2 CYP2D6 mediates 4-hydroxylation of clonidine in vitro: implication for pregnancy-induced changes in clonidine clearance. Drug Metab Dispos. 2010 Sep;38(9):1393-6.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.