Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006603)
Formula Reactant Dabrafenib mesylate Metabolite M26 Product Dabrafenib mesylate Metabolite M28
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006602 M31-Dabrafenib Dabrafenib mesylate Metabolite M26 Unclear Dabrafenib mesylate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006604 Dabrafenib mesylate Metabolite M28 Dabrafenib mesylate Metabolite M29 Unclear Dabrafenib mesylate [1]
References
1 Metabolism and disposition of oral dabrafenib in cancer patients: proposed participation of aryl nitrogen in carbon-carbon bond cleavage via decarboxylation following enzymatic oxidation

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