Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006666)
Formula
SVG example
Oxidationn
Reactant Doxepin hydrochloride Product Doxepin N-oxide
Reactant Info Product Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006668 Doxepin hydrochloride (E)-2-hydroxydoxepin Oxidation - Hydrolyzationn Doxepin hydrochloride [1]
MR006665 Doxepin hydrochloride Formaldehyde Oxidation - N-demethylation Doxepin hydrochloride [2]
MR006661 Doxepin hydrochloride N-desmethyldoxepin Oxidation - N-demethylation Doxepin hydrochloride [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006667 Doxepin N-oxide Doxepin N-oxide glucuronide Conjugation - Glucuronidation Doxepin hydrochloride [2]
References
1 DrugBank(Pharmacology-Metabolism):Doxepin hydrochloride
2 Pharmacogenomics knowledge for personalized medicine Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96.

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