Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006716)
Formula
SVG example
Hydrolyzationn
Reactant 5-hydroxy duloxetine Product Catechol duloxetine
Reactant Info Product Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006715 Duloxetine hydrochloride 5-hydroxy duloxetine Oxidation - Hydrolyzationn Duloxetine hydrochloride [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006721 6-hydroxy duloxetine Catechol duloxetine Oxidation - Hydrolyzationn Duloxetine hydrochloride [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006717 Catechol duloxetine 5-hydroxy, 6-methoxy duloxetine Conjugation - O-methylation Duloxetine hydrochloride [2]
References
1 Duloxetine: clinical pharmacokinetics and drug interactions. Clin Pharmacokinet. 2011 May;50(5):281-94.
2 DrugBank(Pharmacology-Metabolism):Duloxetine

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