Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006872)
Formula Reactant Entacapone Product Entacapone cis-isomer
Reactant Info Product Info
Metabolic Type Other reaction - Isomerization
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006874 Entacapone cis-isomer 3,4-Dihydroxy-5-nitrobenzaldehyde Oxidation - Hydrolyzationn Entacapone [1]
MR006873 Entacapone cis-isomer Entacapone 3-o-glucuronide Conjugation - Glucuronidation Entacapone [2]
References
1 European?Medicines?Agency?(EMA),?Committee?for?Medicinal?Products?for?Human?Use?(CHMP
2 Kinetic characterization of the 1A subfamily of recombinant human UDP-glucuronosyltransferases. Drug Metab Dispos. 2005 Jul;33(7):1017-26.

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