Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006873)
Formula Reactant Entacapone cis-isomer Product Entacapone 3-o-glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006872 Entacapone Entacapone cis-isomer Other reaction - Isomerization Entacapone [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006874 Entacapone cis-isomer 3,4-Dihydroxy-5-nitrobenzaldehyde Oxidation - Hydrolyzationn Entacapone [1]
References
1 European?Medicines?Agency?(EMA),?Committee?for?Medicinal?Products?for?Human?Use?(CHMP

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