Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007079)
Formula
SVG example
Deacylation
Reactant Dapoxetine Product Dapoxetine Metabolite M11
Reactant Info Product Info
Metabolic Type Other reaction - Deacylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007073 Dapoxetine Dapoxetine Metabolite M1 Oxidation - N-dealkylation Dapoxetine [1]
MR007077 Dapoxetine Dapoxetine Metabolite M3 Oxidation - Hydrolyzationn Dapoxetine [1]
MR007083 Dapoxetine Dapoxetine Metabolite M7 Oxidation - Hydrolyzationn Dapoxetine [1]
MR007081 Dapoxetine Dapoxetine-n-oxide Oxidation - Oxidationn Dapoxetine [1]
MR007085 Dapoxetine Didesmethyldapoxetine Unclear Dapoxetine [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007080 Dapoxetine Metabolite M11 Dapoxetine Metabolite M4 Other reaction - Deacylation Dapoxetine [1]
References
1 Characterization of Phase I Hepatic Metabolites of Anti-Premature Ejaculation Drug Dapoxetine by UHPLC-ESI-Q-TOF
2 Dapoxetine: a new option in the medical management of premature ejaculation. Ther Adv Urol. 2012 Oct;4(5):233-51.

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