Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007083)
Formula Reactant Dapoxetine Product Dapoxetine Metabolite M7
Reactant Info Product Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007073 Dapoxetine Dapoxetine Metabolite M1 Oxidation - N-dealkylation Dapoxetine [1]
MR007079 Dapoxetine Dapoxetine Metabolite M11 Other reaction - Deacylation Dapoxetine [1]
MR007077 Dapoxetine Dapoxetine Metabolite M3 Oxidation - Hydrolyzationn Dapoxetine [1]
MR007081 Dapoxetine Dapoxetine-n-oxide Oxidation - Oxidationn Dapoxetine [1]
MR007085 Dapoxetine Didesmethyldapoxetine Unclear Dapoxetine [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007084 Dapoxetine Metabolite M7 Dapoxetine Metabolite M8 Oxidation - Demethylation Dapoxetine [1]
References
1 Characterization of Phase I Hepatic Metabolites of Anti-Premature Ejaculation Drug Dapoxetine by UHPLC-ESI-Q-TOF
2 Dapoxetine: a new option in the medical management of premature ejaculation. Ther Adv Urol. 2012 Oct;4(5):233-51.

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