Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007337)
Formula
UGT
SVG example
Reactant Genistein Product Genistein-7-glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronyltransferase (UGT) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007332 BRN-0064479 Genistein Unclear BRN-0064479 [1]
MR008592 Puerarin Puerarin metabolite M21 Oxidation - Hydroxylation Puerarin [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007347 Genistein 3'-hydroxygenistein Oxidation - 3'-hydroxylation BRN-0064479 [3]
MR007333 Genistein 6'-hydroxy-O-desmethylangolensin Unclear BRN-0064479 [1]
MR007340 Genistein Genistein-4'-glucuronide Unclear BRN-0064479 [3]
MR007345 Genistein Genistein-4'-sulfate Unclear BRN-0064479 [3]
MR007343 Genistein Genistein-7-sulfate Unclear BRN-0064479 [3]
MR008593 Puerarin metabolite M21 Puerarin metabolite M55 Unclear - Unclear Puerarin [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007308 BIO-300 Genistein-7-glucuronide Unclear BIO-300 [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007309 Genistein-7-glucuronide Genistein 7-Glucuronide-4'-Sulfate Unclear BIO-300 [3]
MR007310 Genistein-7-glucuronide Genistein-4',7-diglucuronide Unclear BIO-300 [3]
MR007338 Genistein-7-glucuronide Genistein 7-Glucuronide-4'-Sulfate Unclear BRN-0064479 [3]
MR007339 Genistein-7-glucuronide Genistein-4',7-diglucuronide Unclear BRN-0064479 [3]
References
1 Comparative metabolism of genistin by human and rat gut microflora: detection and identification of the end-products of metabolism
2 Rapid profiling and identification of puerarin metabolites in rat urine and plasma after oral administration by UHPLC-LTQ-Orbitrap mass spectrometer
3 Genistein: Dual Role in Women's Health

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