Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007632)
Formula
UGT1A3 ...
SVG example
Acyl glucuronidation
Reactant ML-3000 Product Licofelone acyl glucuronide (M1)
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A3 (UGT1A3) DME Info
UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
Metabolic Type Conjugation - Acyl glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007634 ML-3000 Licofelone M2 Oxidation - Hydrolyzationn ML-3000 [1]
MR007630 ML-3000 Licofelone M4 Oxidation - Hydrolyzationn ML-3000 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007633 Licofelone acyl glucuronide (M1) Licofelone M3 Oxidation - Hydrolyzationn ML-3000 [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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