Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007693)
Formula
SVG example
S-methylation
Reactant 7alpha-methylsulfonylSpirolactone Product 7alpha-thiomethylspironolactone
Reactant Info Product Info
Metabolic Type Conjugation - S-methylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007692 7alpha-methylsulfinylSpirolactone 7alpha-methylsulfonylSpirolactone Oxidation - S-oxidation Spironolactone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007695 7alpha-thiomethylspironolactone 3alpha-hydroxythiomethylspironolactone Reduction - Reduction Spironolactone [2]
MR007694 7alpha-thiomethylspironolactone 3beta-hydroxythiomethylspironolactone Reduction - Reduction Spironolactone [2]
References
1 The metabolism and biopharmaceutics of spironolactone in man
2 DrugBank(Pharmacology-Metabolism):Spironolactone

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