Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008535)
Formula
SVG example
Hydrolysis
Reactant TH-302 metabolite RM9 Product TH-302 metabolite RM10
Reactant Info Product Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008526 TH-302 TH-302 metabolite RM9 Conjugation - Glutathione conjugation TH-302 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008534 TH-302 metabolite RM9 TH-302 metabolite RM5 Hydrolysis - Hydrolysis TH-302 [1]
MR008533 TH-302 metabolite RM9 TH-302 metabolite RM6 Oxidation - Oxidation TH-302 [1]
MR008527 TH-302 metabolite RM9 TH-302 metabolite RM7 Hydrolysis - Hydrolysis TH-302 [1]
References
1 Metabolism, pharmacokinetics and excretion of a novel hypoxia activated cytotoxic prodrug, TH-302, in rats

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