Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008754)
Formula
SVG example
Esterase hydrolysis
Reactant Benzocaine Product Aminobenzoic acid
Reactant Info Product Info
Metabolic Type Hydrolysis - Esterase hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008756 Benzocaine Acetylbenzocaine Conjugation - Acetylation Benzocaine [1]
MR008758 Benzocaine Benzocaine hydroxylamine Oxidation - N-hydroxylation Benzocaine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007603 p-nitrobenzoic acid PABA Reduction - Reduction P-nitrobenzoic acid [2]
MR010593 Tetracaine Para-aminobenzoic acid Unclear - Unclear Tetracaine [3]
References
1 More methemoglobin is produced by benzocaine treatment than lidocaine treatment in human in vitro systems
2 Evaluation of a simple in-house test to presumptively differentiate Mycobacterium tuberculosis complex from nontuberculous mycobacteria by detection of p-nitrobenzoic acid metabolites
3 Characterization of seven new related impurities and forced degradation products of tetracaine hydrochloride and proposal of degradation pathway by UHPLC-Q-TOF-MS

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