Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008758)
Formula
CYP1A2 ...
SVG example
N-hydroxylation
Reactant Benzocaine Product Benzocaine hydroxylamine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 2E1 (CYP2E1) DME Info
Metabolic Type Oxidation - N-hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008756 Benzocaine Acetylbenzocaine Conjugation - Acetylation Benzocaine [1]
MR008754 Benzocaine Aminobenzoic acid Hydrolysis - Esterase hydrolysis Benzocaine [1]
References
1 More methemoglobin is produced by benzocaine treatment than lidocaine treatment in human in vitro systems

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