Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008877)
Formula
SVG example
Sulfate conjugation
Reactant Lasofoxifene Product Lasofoxifene metabolite M11
Reactant Info Product Info
Metabolic Type Conjugation - Sulfate conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008875 Lasofoxifene 5-hydroxy-lasofoxifene (5-OHLAS) Oxidation - 5-hydroxylation Lasofoxifene [1]
MR008874 Lasofoxifene 7-hydroxy-lasofoxifene (7-OHLAS) Oxidation - 7-hydroxylation Lasofoxifene [1]
MR008878 Lasofoxifene Lasofoxifene metabolite M13 Unclear - Unclear Lasofoxifene [2]
MR008872 Lasofoxifene Lasofoxifene metabolite M15 Unclear - Unclear Lasofoxifene [2]
MR008876 Lasofoxifene Lasofoxifene metabolite M7 Unclear - Unclear Lasofoxifene [2]
References
1 Disposition of lasofoxifene, a next-generation selective estrogen receptor modulator, in healthy male subjects
2 Metabolism, distribution, and excretion of a next generation selective estrogen receptor modulator, lasofoxifene, in rats and monkeys

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