Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009091)
Formula
CYP2D6 ...
SVG example
Oxidation; deamination
Reactant Fidarestat Product Fidarestat Metabolite F1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Multi-steps Reaction - Oxidation; deamination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009104 Fidarestat Fidarestat Metabolite F11 Multi-steps Reaction - Hydroxylation; glycosylation Fidarestat [1]
MR009101 Fidarestat Fidarestat Metabolite F14 Other reaction - Cysteamination Fidarestat [1]
MR009106 Fidarestat Fidarestat Metabolite F15 Multi-steps Reaction - Hydroxylation; cysteamination Fidarestat [1]
MR009105 Fidarestat Fidarestat Metabolite F16 Conjugation - N-acetylation Fidarestat [1]
MR009102 Fidarestat Fidarestat Metabolite F17 Oxidation - Dihydroxylation Fidarestat [1]
MR009103 Fidarestat Fidarestat Metabolite F18 Conjugation - Glucuronidation Fidarestat [1]
MR009097 Fidarestat Fidarestat Metabolite F3 Multi-steps Reaction - Reduction; defluroniation Fidarestat [1]
MR009107 Fidarestat Fidarestat Metabolite F4 Reduction - Hydrogenation Fidarestat [1]
MR009108 Fidarestat Fidarestat Metabolite F5 Oxidation - Trihydroxylation Fidarestat [1]
MR009100 Fidarestat Fidarestat Metabolite F6 Oxidation - Methylation Fidarestat [1]
MR009099 Fidarestat Fidarestat Metabolite F8 Multi-steps Reaction - Oxidation; acetylation Fidarestat [1]
MR009098 Fidarestat Fidarestat Metabolite F9 Conjugation - Glycosylation Fidarestat [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009096 Fidarestat Metabolite F1 Fidarestat Metabolite F10 Conjugation - Glycosylation Fidarestat [1]
MR009094 Fidarestat Metabolite F1 Fidarestat Metabolite F12 Conjugation - Glucuronidation Fidarestat [1]
MR009092 Fidarestat Metabolite F1 Fidarestat Metabolite F2 Oxidation - Hydroxylation Fidarestat [1]
MR009095 Fidarestat Metabolite F1 Fidarestat Metabolite F7 Conjugation - Acetylation Fidarestat [1]
References
1 Identification and characterization of in vitro and in vivo fidarestat metabolites: Toxicity and efficacy evaluation of metabolites

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