Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009200)
Formula
SVG example
Unclear
Reactant 3-(Dihydroxyphenyl)propanoic acid Product DHFA
Reactant Info Product Info
Metabolic Enzyme Catechol O-methyltransferase (COMT) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009194 3,4-Dihydroxycinnamic Acid 3-(Dihydroxyphenyl)propanoic acid Reduction - Reduction 3,4-Dihydroxycinnamic Acid [1], [2]
MR013001 Perillic acid (PCOOH) Cis-Dihydroperillic Acid Unclear - Unclear Perillyl alcohol [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009195 3-(Dihydroxyphenyl)propanoic acid 3-(3'-Hydroxyphenyl)propanoic acid Oxidation - Dehydroxylation 3,4-Dihydroxycinnamic Acid [1]
MR009202 3-(Dihydroxyphenyl)propanoic acid O-quinone Unclear - Unclear 3,4-Dihydroxycinnamic Acid [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006954 AS-63093 4-hydroxy- 4-Hydroxyphenylpropionic acid Unclear AS-63093 [4]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009201 DHFA FA Unclear - Unclear 3,4-Dihydroxycinnamic Acid [2]
References
1 In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota
2 Metabolism of caffeic acid by isolated rat hepatocytes and subcellular fractions
3 Gas chromatographic-mass spectrometric analysis of perillyl alcohol and metabolites in plasma
4 Studies on pharmacokinetic drug interaction potential of vinpocetine. Medicines (Basel). 2015 Jun 5;2(2):93-105.

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