Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009202)
Formula	CYP2E1 Unclear
	Reactant	3-(Dihydroxyphenyl)propanoic acid	Product	O-quinone
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 2E1 (CYP2E1)				DME Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR009194	3,4-Dihydroxycinnamic Acid	3-(Dihydroxyphenyl)propanoic acid	Reduction - Reduction	3,4-Dihydroxycinnamic Acid	[1], [2]
MR013001	Perillic acid (PCOOH)	Cis-Dihydroperillic Acid	Unclear - Unclear	Perillyl alcohol	[3]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR009195	3-(Dihydroxyphenyl)propanoic acid	3-(3'-Hydroxyphenyl)propanoic acid	Oxidation - Dehydroxylation	3,4-Dihydroxycinnamic Acid	[1]
MR009200	3-(Dihydroxyphenyl)propanoic acid	DHFA	Unclear - Unclear	3,4-Dihydroxycinnamic Acid	[2]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR000253	Apomorphine	O-quinone	Oxidation - Oxidation	Apomorphine	[4]
MR007624	Pyrocatechol	O-quinone	Unclear	Pyrocatechol	[5]

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR007625	O-quinone	Unclear	Conjugation - Conjugation	Pyrocatechol	[5]

References
1	In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota
2	Metabolism of caffeic acid by isolated rat hepatocytes and subcellular fractions
3	Gas chromatographic-mass spectrometric analysis of perillyl alcohol and metabolites in plasma
4	DrugBank(Pharmacology-Metabolism)Apomorphine
5	Assessment of the metabolism and intrinsic reactivity of a novel catechol metabolite

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