Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009525)
Formula Reactant Revefenacin Product THRX-195518
Reactant Info Product Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009528 Revefenacin THRX-177860 Multi-steps Reaction - N-dealkylation; oxidation Revefenacin [1]
MR009527 Revefenacin THRX-609075 Hydrolysis - Hydrolysis Revefenacin [1]
MR009529 Revefenacin THRX-697795 Multi-steps Reaction - N-dealkylation; reduction Revefenacin [1]
MR009530 Revefenacin Unclear Unclear - Unclear Revefenacin [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009526 THRX-195518 THRX-193305 Oxidation - N-dealkylation Revefenacin [1]
References
1 Revefenacin Absorption, Metabolism, and Excretion in Healthy Subjects and Pharmacological Activity of Its Major Metabolite
2 A 28-day, randomized, double-blind, placebo-controlled, parallel group study of nebulized revefenacin in patients with chronic obstructive pulmonary disease. Respir Res. 2017 Nov 2;18(1):182.

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