Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009528)
Formula Reactant Revefenacin Product THRX-177860
Reactant Info Product Info
Metabolic Type Multi-steps Reaction - N-dealkylation; oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009525 Revefenacin THRX-195518 Hydrolysis - Hydrolysis Revefenacin [1]
MR009527 Revefenacin THRX-609075 Hydrolysis - Hydrolysis Revefenacin [1]
MR009529 Revefenacin THRX-697795 Multi-steps Reaction - N-dealkylation; reduction Revefenacin [1]
MR009530 Revefenacin Unclear Unclear - Unclear Revefenacin [2]
References
1 Revefenacin Absorption, Metabolism, and Excretion in Healthy Subjects and Pharmacological Activity of Its Major Metabolite
2 A 28-day, randomized, double-blind, placebo-controlled, parallel group study of nebulized revefenacin in patients with chronic obstructive pulmonary disease. Respir Res. 2017 Nov 2;18(1):182.

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