Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009588)
Formula	Sulfonation
	Reactant	Ortho-Hydroxyrosiglitazone	Product	Ortho-O-Sulfate rosiglitazone
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - Sulfonation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR009586	Rosiglitazone	Ortho-Hydroxyrosiglitazone	Oxidation - Hydroxylation	Rosiglitazone	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR009587	Ortho-Hydroxyrosiglitazone	N-Desmethyl-ortho-hydroxy rosiglitazone	Oxidation - N-demethylation	Rosiglitazone	[1]
MR009589	Ortho-Hydroxyrosiglitazone	Ortho-O-Glucuronide rosiglitazone	Conjugation - Glucuronidation	Rosiglitazone	[1]

References
1	Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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