Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009612)
Formula
SVG example
Unclear
Reactant Siponimod M2 Product Siponimod M1
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009611 BAF-312 Siponimod M2 Unclear - Unclear BAF-312 [1]
MR002274 Siponimod Siponimod metabolite M2 Unclear Siponimod [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009621 BAF-312 Siponimod M1 Unclear - Unclear BAF-312 [1]
MR002272 Siponimod Siponimod metabolite M1 Oxidation - Hydroxylation Siponimod [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009613 Siponimod M1 Siponimod M8 Unclear - Unclear BAF-312 [1]
References
1 Metabolism and disposition of siponimod, a novel selective S1P1/S1P5 agonist, in healthy volunteers and in vitro identification of human cytochrome P450 enzymes involved in its oxidative metabolism. Drug Metab Dispos. 2018 Jul;46(7):1001-1013.

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