Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009613)
Formula
SVG example
Unclear
Reactant Siponimod M1 Product Siponimod M8
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009621 BAF-312 Siponimod M1 Unclear - Unclear BAF-312 [1]
MR002272 Siponimod Siponimod metabolite M1 Oxidation - Hydroxylation Siponimod [1]
MR009612 Siponimod M2 Siponimod M1 Unclear - Unclear BAF-312 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002275 Siponimod Siponimod metabolite M8 Unclear Siponimod [1]
References
1 Metabolism and disposition of siponimod, a novel selective S1P1/S1P5 agonist, in healthy volunteers and in vitro identification of human cytochrome P450 enzymes involved in its oxidative metabolism. Drug Metab Dispos. 2018 Jul;46(7):1001-1013.

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