Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009617)
Formula
SVG example
Sulfonation
Reactant Siponimod M6 Product Siponimod M4c
Reactant Info Product Info
Metabolic Type Oxidation - Sulfonation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009616 BAF-312 Siponimod M6 Oxidation - Hydroxylation BAF-312 [1]
MR002271 Siponimod Siponimod metabolite M6 Unclear Siponimod [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002268 Siponimod metabolite M6 Siponimod metabolite M4C Unclear Siponimod [1]
References
1 Metabolism and disposition of siponimod, a novel selective S1P1/S1P5 agonist, in healthy volunteers and in vitro identification of human cytochrome P450 enzymes involved in its oxidative metabolism. Drug Metab Dispos. 2018 Jul;46(7):1001-1013.

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