Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009661)
Formula
SVG example
N-deethylation
Reactant AD-5423 Product N-desethyl blonanserin
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A1 (CYP1A1) DME Info
Metabolic Type Oxidation - N-deethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009664 AD-5423 Blonanserin M5 Oxidation - Hydroxylation AD-5423 [1]
MR009666 AD-5423 Blonanserin M7 Oxidation - Hydroxylation AD-5423 [1]
MR009668 AD-5423 N-oxidation blonanserin Oxidation - N-oxidation AD-5423 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009662 N-desethyl blonanserin Blonanserin M3 Oxidation - N-deethylation AD-5423 [2]
References
1 Blonanserin: a review of its use in the management of schizophrenia
2 Simultaneous determination of blonanserin and its four metabolites in human plasma using ultra-performance liquid chromatography-tandem mass spectrometry

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