Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009666)
Formula Reactant AD-5423 Product Blonanserin M7
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A1 (CYP1A1) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009664 AD-5423 Blonanserin M5 Oxidation - Hydroxylation AD-5423 [1]
MR009661 AD-5423 N-desethyl blonanserin Oxidation - N-deethylation AD-5423 [2]
MR009668 AD-5423 N-oxidation blonanserin Oxidation - N-oxidation AD-5423 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009667 Blonanserin M7 Blonanserin M8 Conjugation - Glucuronidation AD-5423 [1]
References
1 Blonanserin: a review of its use in the management of schizophrenia
2 Simultaneous determination of blonanserin and its metabolite in human plasma and urine by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study

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