Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009673)
Formula
SVG example
Reduction
Reactant Dihydrocurcumin Product Tetrahydrocurcumin
Reactant Info Product Info
Metabolic Enzyme NADPH-dependent curcumin reductase (curA) DME Info
Metabolic Type Reduction - Reduction
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009669 Curcumin Dihydrocurcumin Reduction - Reduction Curcumin [1], [2], [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009670 Dihydrocurcumin Dihydrocurcumin bate-O-glucuronide Conjugation - Glucuronidation Curcumin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009675 Tetrahydrocurcumin Hexahydrocurcumin Reduction - Reduction Curcumin [1], [2], [3]
MR009674 Tetrahydrocurcumin Tetrahydrocurcumin bate-O-glucuronide Conjugation - Glucuronidation Curcumin [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 Curcumin, Gut Microbiota, and Neuroprotection
3 Curcumin and Weight Loss: Does It Work?

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