Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009674)
Formula
SVG example
Glucuronidation
Reactant Tetrahydrocurcumin Product Tetrahydrocurcumin bate-O-glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 2A1 (UGT2A1) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009673 Dihydrocurcumin Tetrahydrocurcumin Reduction - Reduction Curcumin [1], [2], [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009675 Tetrahydrocurcumin Hexahydrocurcumin Reduction - Reduction Curcumin [1], [2], [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009671 Dihydrocurcumin bate-O-glucuronide Tetrahydrocurcumin bate-O-glucuronide Reduction - Reduction Curcumin [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009672 Tetrahydrocurcumin bate-O-glucuronide Hexahydrocurcumin bate-O-glucuronide Reduction - Reduction Curcumin [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 Curcumin, Gut Microbiota, and Neuroprotection
3 Curcumin and Weight Loss: Does It Work?

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