Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009838)
Formula Reactant Alpelisib Metabolite M4 Product Alpelisib Metabolite M8
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009837 Alpelisib Alpelisib Metabolite M4 Unclear - Unclear Alpelisib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009839 Alpelisib Metabolite M4 Alpelisib Metabolite M19 Unclear - Unclear Alpelisib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009836 Alpelisib Metabolite M3 Alpelisib Metabolite M8 Oxidation - Oxidation Alpelisib [1]
References
1 Absorption, distribution, metabolism, and excretion of [(14)C]BYL719 (alpelisib) in healthy male volunteers. Cancer Chemother Pharmacol. 2015 Oct;76(4):751-60.

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