Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009844)
Formula	Unclear
	Reactant	Alprazolam	Product	5-N-O?alprazolam
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR009846	Alprazolam	4-hydroxyalprazolam	Unclear - Unclear	Alprazolam	[1], [2]
MR009848	Alprazolam	Alpha-hydroxyalprazolam	Unclear - Unclear	Alprazolam	[2]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR009845	5-N-O?alprazolam	6-Keto?alprazolam	Unclear - Unclear	Alprazolam	[3]

References
1	Alprazolam metabolism in vitro: studies of human, monkey, mouse, and rat liver microsomes
2	Drug metabolism in human brain: high levels of cytochrome P4503A43 in brain and metabolism of anti-anxiety drug alprazolam to its active metabolite
3	Changes in Alprazolam Metabolism by CYP3A43 Mutants

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