Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010504)
Formula
SVG example
Dehydrogenation Hydroxylation
Reactant ACU-5116 Product ACU-5188
Reactant Info Product Info
Metabolic Type Oxidation - Dehydrogenation Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010499 Emixustat ACU-5116 Oxidation - Oxidative Deamination Emixustat [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010500 ACU-5116 ACU-5124 Oxidation - Hydroxylation Emixustat [1], [2]
MR010502 ACU-5116 ACU-5144 Oxidation - Hydroxylation Emixustat [1], [2]
MR010503 ACU-5116 ACU-5145 Oxidation - Hydroxylation Emixustat [1], [2]
MR010501 ACU-5116 ACU-5149 Oxidation - Hydroxylation Emixustat [1], [2]
References
1 Oxidative Deamination of Emixustat by Human Vascular Adhesion Protein-1/Semicarbazide-Sensitive Amine Oxidase
2 Disposition, profiling and identification of emixustat and its metabolites in humans

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