Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011203)
Formula Reactant Hydromorphol Product Hydrocodone M274
Reactant Info Product Info
Metabolic Type Oxidation - N-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011202 Hydromorphone Hydromorphol Reduction - Ketone reduction Hydrocodone [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011208 Hydromorphol Hydrocodone M286 Multi-steps Reaction - Possible combination of hydroxylation; dehydration Hydrocodone [1]
MR011209 Hydromorphol Hydrocodone M464 Conjugation - Glucuronidation Hydrocodone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR014001 Hydrocodone M272 Hydrocodone M274 Oxidation - N-demethylation Hydrocodone [1]
MR011207 Hydrocodone M272 Hydrocodone M274 Oxidation - N-demethylation Hydrocodone [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR014002 Hydrocodone M274 Hydrocodone M450 Conjugation - Glucuronidation Hydrocodone [1]
MR011204 Hydrocodone M274 Hydrocodone M450 Conjugation - Glucuronidation Hydrocodone [1]
References
1 Update on hydrocodone metabolites in rats and dogs aided with a semi-automatic software for metabolite identification Mass-MetaSite

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