Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011486)
Formula Reactant Naldemedine carboxylic acid Product MS486
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011485 S-297995 Naldemedine carboxylic acid Hydrolysis - Hydrolysis S-297995 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011488 Naldemedine carboxylic acid MS416 Oxidation - N-dealkylation S-297995 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011487 MS486 MS502 Oxidation - Oxidation S-297995 [1]
References
1 Absorption, distribution, metabolism, and excretion of radiolabeled naldemedine in healthy subjects

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