Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011485)
Formula
SVG example
Hydrolysis
Reactant S-297995 Product Naldemedine carboxylic acid
Reactant Info Product Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011491 S-297995 Benzamidine Multi-steps Reaction - Reduction; Hydrolysis S-297995 [1]
MR011493 S-297995 Naidemedine-(7R)-7-hydroxide Oxidation - Oxidation S-297995 [1]
MR011494 S-297995 Naidemedine-(7S)-7-hydroxide Oxidation - Oxidation S-297995 [1]
MR011495 S-297995 Naidemedine-3-G Conjugation - Glucuronide conjugation S-297995 [1]
MR011489 S-297995 Nor-naldemedine Oxidation - N-dealkylation S-297995 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011488 Naldemedine carboxylic acid MS416 Oxidation - N-dealkylation S-297995 [1]
MR011486 Naldemedine carboxylic acid MS486 Oxidation - Oxidation S-297995 [1]
References
1 Absorption, distribution, metabolism, and excretion of radiolabeled naldemedine in healthy subjects

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.