Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011786)
Formula
SVG example
Demethylation
Reactant Telapristone Product Monodemethylated telapristone
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Oxidation - Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011788 Telapristone 17alpha-Hydroxy telapristone Oxidation - Hydroxylation Telapristone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011787 Monodemethylated telapristone Didemethylated telapristone Oxidation - Demethylation Telapristone [1]
References
1 Population pharmacokinetics of telapristone (CDB-4124) and its active monodemethylated metabolite CDB-4453, with a mixture model for total clearance

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