Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011787)
Formula	CYP3A5 Demethylation
	Reactant	Monodemethylated telapristone	Product	Didemethylated telapristone
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A5 (CYP3A5)				DME Info
Metabolic Type	Oxidation - Demethylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR011786	Telapristone	Monodemethylated telapristone	Oxidation - Demethylation	Telapristone	[1]

References
1	Population pharmacokinetics of telapristone (CDB-4124) and its active monodemethylated metabolite CDB-4453, with a mixture model for total clearance

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