Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012431)
Formula Reactant AZD8931 M18 Product AZD8931 M1
Reactant Info Product Info
Metabolic Type Conjugation - O-despiperidinyl glucosidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012429 AZD8931 AZD8931 M18 Oxidation - O-despiperidine AZD8931 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012430 AZD8931 M18 AZD8931 M5 Conjugation - O-despiperidinyl sulfation AZD8931 [1]
References
1 Metabolic disposition of AZD8931, an oral equipotent inhibitor of EGFR, HER2 and HER3 signalling, in rat, dog and man

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