Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012670)
Formula
SVG example
N-demethylation
Reactant LY-333531 Product N-desmethyl ruboxistaurin
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A (CYP3A) DME Info
Metabolic Type Oxidation - N-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012672 LY-333531 Ruboxistaurin metabolite 3 Oxidation - Hydroxylation LY-333531 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012671 N-desmethyl ruboxistaurin Ruboxistaurin metabolite 5 Oxidation - Hydroxylation LY-333531 [1]
References
1 Disposition of [14C]ruboxistaurin in humans

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