Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012677)
Formula
SVG example
Hydroxylation
Reactant MGI-114 Product Irofulven metabolite 4 (M4)
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012689 MGI-114 Irofulven metabolite 3 (M3) Oxidation - Hydroxylation MGI-114 [1]
MR012680 MGI-114 Irofulven metabolite 6 (M6) Unclear - Unclear MGI-114 [1]
MR012687 MGI-114 Irofulven-glucuronide conjugate (M') Conjugation - Glucuronidation MGI-114 [1]
MR012688 MGI-114 Irofulven-glutathione conjugate (M1) Conjugation - Glutathione conjugation MGI-114 [1]
MR012682 MGI-114 Opened-ring metabolite (M2) Unclear - Unclear MGI-114 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012678 Irofulven metabolite 4 (M4) Irofulven metabolite 5 (M5) Unclear - Unclear MGI-114 [1]
MR012686 Irofulven metabolite 4 (M4) M4-glucuronide conjugate (M'4) Conjugation - Glucuronidation MGI-114 [1]
References
1 Pharmacokinetics, metabolism, and routes of excretion of intravenous irofulven in patients with advanced solid tumors

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.