Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012687)
Formula Reactant MGI-114 Product Irofulven-glucuronide conjugate (M')
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012689 MGI-114 Irofulven metabolite 3 (M3) Oxidation - Hydroxylation MGI-114 [1]
MR012677 MGI-114 Irofulven metabolite 4 (M4) Oxidation - Hydroxylation MGI-114 [1]
MR012680 MGI-114 Irofulven metabolite 6 (M6) Unclear - Unclear MGI-114 [1]
MR012688 MGI-114 Irofulven-glutathione conjugate (M1) Conjugation - Glutathione conjugation MGI-114 [1]
MR012682 MGI-114 Opened-ring metabolite (M2) Unclear - Unclear MGI-114 [1]
References
1 Pharmacokinetics, metabolism, and routes of excretion of intravenous irofulven in patients with advanced solid tumors

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