Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012870)
Formula
SVG example
Reactant Normorphine Product Normorphine-3-glucuronide
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004806 Morphine Normorphine Oxidation - Demethylation Morphine [1]
MR004099 Morphine Normorphine Conjugation - Glucuronidation Codeine [2]
MR012869 Morphine Normorphine Unclear Ethylmorphine [3]
MR004095 Norcodeine Normorphine Oxidation - O-demethylation Codeine [4]
MR012873 Norethylmorphine Normorphine Unclear Ethylmorphine [3]
MR013334 Morphine Normorphine Oxidation - Demethylation Heroin [1]
⏷ Show the Full List of MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012871 Normorphine Normorphine-6-glucuronide Unclear Ethylmorphine [3]
⏷ Show the Full List of MR
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012876 Norethylmorphine Normorphine-3-glucuronide Conjugation - Glucuronidation Ethylmorphine [5]
References
1 Morphine: pharmacokinetics and clinical practice
2 Diclofenac does not interact with codeine metabolism in vivo: a study in healthy volunteers
3 Biotransformation and pharmacokinetics of ethylmorphine after a single oral dose. Br J Clin Pharmacol. 1995 Jun;39(6):611-20.
4 Pharmacogenetics of analgesic drugs
5 Ethylmorphine metabolism in isolated rat hepatocytes

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.