Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012873)
Formula
SVG example
Reactant Norethylmorphine Product Normorphine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012872 Ethylmorphine Norethylmorphine Unclear Ethylmorphine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012877 Norethylmorphine Norethylmorphine-6-glucuronide Unclear Ethylmorphine [2]
MR012876 Norethylmorphine Normorphine-3-glucuronide Conjugation - Glucuronidation Ethylmorphine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004806 Morphine Normorphine Oxidation - Demethylation Morphine [3]
MR004099 Morphine Normorphine Conjugation - Glucuronidation Codeine [4]
MR012869 Morphine Normorphine Unclear Ethylmorphine [2]
MR004095 Norcodeine Normorphine Oxidation - O-demethylation Codeine [5]
MR013334 Morphine Normorphine Oxidation - Demethylation Heroin [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012870 Normorphine Normorphine-3-glucuronide Unclear Ethylmorphine [2]
MR012871 Normorphine Normorphine-6-glucuronide Unclear Ethylmorphine [2]
References
1 Ethylmorphine metabolism in isolated rat hepatocytes
2 Biotransformation and pharmacokinetics of ethylmorphine after a single oral dose. Br J Clin Pharmacol. 1995 Jun;39(6):611-20.
3 Morphine: pharmacokinetics and clinical practice
4 Diclofenac does not interact with codeine metabolism in vivo: a study in healthy volunteers
5 Pharmacogenetics of analgesic drugs

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