Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013099)
Formula
SVG example
Oxidation
Reactant ABT-333 Product ABT-333 Metabolite M1
Reactant Info Product Info
Metabolic Enzyme DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013110 ABT-333 Metabolite M1 ABT-333 Metabolite M11 Oxidation - Oxidation ABT-333 [1]
MR013108 ABT-333 Metabolite M1 ABT-333 Metabolite M2 Conjugation - Conjugation ABT-333 [1]
MR013105 ABT-333 Metabolite M1 ABT-333 Metabolite M3 Unclear - Unclear ABT-333 [1]
MR013100 ABT-333 Metabolite M1 ABT-333 Metabolite M4 Oxidation - Oxidation ABT-333 [1]
MR013106 ABT-333 Metabolite M1 ABT-333 Metabolite M9 Reduction - Reduction ABT-333 [1]
References
1 Metabolism and disposition of hepatitis C polymerase inhibitor dasabuvir in humans. Drug Metab Dispos. 2016 Aug;44(8):1139-47.

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