Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013312)
Formula
SVG example
Reactant 16-alpha hydroxyestrone Product Estriol
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013310 Estrone 16-alpha hydroxyestrone Unclear E-3A [1]
MR002645 Estrone 16alpha hydroxyestrone Unclear Estradiol acetate [1]
MR002668 Estrone 16alpha hydroxyestrone Unclear Estradiol cypionate [1]
MR002691 Estrone 16alpha hydroxyestrone Unclear Estradiol valerate [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013311 16-alpha hydroxyestrone 17-Epiestriol Unclear E-3A [1]
MR002638 16alpha hydroxyestrone 17-Epiestriol Unclear Estradiol acetate [1]
MR002661 16alpha hydroxyestrone 17-Epiestriol Unclear Estradiol cypionate [1]
MR002684 16alpha hydroxyestrone 17-Epiestriol Unclear Estradiol valerate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004242 Estrone sulfate Estriol Unclear Estrone sulfate [2]
MR000966 Estropipate Estriol Unclear Estropipate [3]
MR004102 Estrone Estriol Oxidation - Hydrolyzationn Conjugated estrogens [4]
MR003144 17-beta-estradiol Estriol Unclear Dehydroepiandrosterone [5]
References
1 Cytochrome P450 1A2 (CYP1A2) activity and risk factors for breast cancer: a cross-sectional study. Breast Cancer Res. 2004;6(4):R352-65.
2 DrugBank(Pharmacology-Metabolism):Estrone sulfate
3 DrugBank(Pharmacology-Metabolism)Estropipate
4 DrugBank(Pharmacology-Metabolism):Conjugated estrogens
5 Resveratrol Inhibits Key Steps of Steroid Metabolism in a Human Estrogen-Receptor Positive Breast Cancer Model: Impact on Cellular Proliferation Front Pharmacol. 2018 Jul 10;9:742. doi: 10.3389/fphar.2018.00742.

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